Post-Doctoral Associate

Position Summary: We are seeking a highly motivated recent or pending MD and/or PhD graduate to work in a molecular and cellular neuroscience/stem cell lab for disease modeling using patient-derived induced pluripotent stem cells (iPSC). The Post-Doctoral Associate will use a multi-pronged approach including biochemistry, CRISPR genetic editing, gene expression analysis, proteomics, and imaging. The ideal candidate will have experience in cell culture, rodents, biochemical, molecular and cellular biological techniques in neuroscience or stem cell biology.

Work Schedule: In-person, 5 days a week, and 40 hours a week.

Duties/Responsibilities:
As a Post-Doctoral Associate, you will work in a molecular and cellular neuroscience/stem cell lab for disease modeling using patient derived induced pluripotent stem cells (iPSC). Our research goals are to further our understanding of the pathophysiology of neurodegenerative diseases and to identify novel pathways and targets for the development of therapy. In particular, we are interested in understanding the mechanisms underlying protein misfolding, extracellular vesicles and propagation of disease in neurodegeneration. We use iPSC from patients with Alzheimer's Disease and other types of neurodegenerative diseases as our model system, in additional to genetically modified mice.

The Post-Doctoral Associate will use multi-pronged approach including biochemistry, CRISPR genetic editing, gene expression analysis, mouse genetics, proteomics and imaging. The University of Minnesota provides an excellent environment for stem cell and neurodegeneration research, with the University of Stem Cell Institute and the N. Bud Grossman Center for Memory Research and Care.

Required Qualifications:

• Holds a Ph.D.

Preferred Qualifications:

• Experience with cell culture.
• Experience with working with rodent models.

Our research goals are to further our understanding of the pathophysiology of neurodegenerative diseases and to identify novel pathways and targets for the development of therapy. In particular, we are interested in understanding the mechanisms of genetic risk variants and protective variants. We use induced pluripotent stem cells (iPSCs) from patients with Alzheimer's Disease and other types of neurodegenerative diseases as our model system. To learn more about the Department of Neurology, please visit https://med.umn.edu/neurology.

Pay Range: $63,480 - $77,076 annually; depending on education/qualifications/experience

Please visit the Benefits for Postdoctoral Candidates website for more information regarding benefit eligibility.

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training
• Medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and life insurance
• Employee wellbeing program
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail jobcentr@umn.edu.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by Forbes as a Best Employer for Company Culture (2026), Best Employer for Women (2023, 2025, 2026), and Best Employer by State (2022-2026). In 2026, we also received Culture Excellence & Industry Awards recognition for employee appreciation and work-life flexibility.