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Phathom Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of gastrointestinal (GI) diseases. With exclusive rights in the United States, Europe, and Canada to vonoprazan—a first-in-class potassium-competitive acid blocker (PCAB)—Phathom is working to transform the treatment of acid-related disorders.
Our Current Portfolio Includes
- VOQUEZNA® (vonoprazan) tablets, approved for the treatment of heartburn associated with Non-Erosive GERD, as well as the healing and maintenance of healing of Erosive GERD
- VOQUEZNA® TRIPLE PAK® (vonoprazan tablets, amoxicillin capsules, clarithromycin tablets) and VOQUEZNA® DUAL PAK® (vonoprazan tablets, amoxicillin capsules), approved for the treatment of H. pylori infection in adults
Beyond our commercialized products, we are advancing a pipeline focused on innovative treatments for other acid-related GI disorders, including Eosinophilic Esophagitis (EoE).
At Phathom, we are fueled by innovation, driven by purpose, and united by a shared commitment to improving patient outcomes. Our team comprises seasoned GI and industry experts with proven track records of delivering groundbreaking therapies, including anti-secretory agents. Together, we are tackling unmet medical needs and working hard to enhance the lives of patients.
We seek motivated, innovative problem-solvers who excel in fast-paced, collaborative environments and are eager to make an impact. At Phathom, you’ll find more than a career – you’ll join our “Phamily,” where employees feel empowered, valued, and inspired to do their best work.
In August 2025, we proudly earned the distinction of being Great Place to Work® certified, with 91% of surveyed employees affirming that Phathom is an exceptional workplace.
Ready to help change the landscape in GI? Join us and be part of something extraordinary.
OBJECTIVES
- To provide senior-level medical and scientific leadership within the Promotional Review Committee (PRC) and Medical Review Committee (MRC), ensuring strategic, scientifically accurate, and compliant promotional and non-promotional materials.
- To oversee the Medical Information strategy and ensure the development of high-quality, balanced, and scientifically rigorous medical information responses for HCPs and patients.
- To serve as a senior therapeutic-area expert, maintaining deep knowledge of clinical evidence, competitive landscape, treatment guidelines, and unmet needs to inform brand and medical strategy.
- To guide cross-functional teams (Commercial, Legal, Regulatory, R&D) in developing scientifically supportable claims, identifying evidence gaps, and shaping data-generation needs.
Accountabilities
- Leads Medical Affairs representation in PRC/MRC, providing authoritative medical assessment of claims, references, data relevance, and scientific rigor.
- Ensures promotional materials reflect accurate, balanced, and supportable scientific content and provides proactive recommendations for compliant claim alternatives.
- Oversees Medical Information content development, including standard response letters, escalated inquiries, and cross-functional alignment of medical messaging.
- Partners with Commercial, Regulatory, Legal, and R&D colleagues to support brand strategy, future claim feasibility, and risk-mitigation planning.
- Maintains subject matter expertise in disease state, guidelines, and competitive intelligence to inform internal teams and influence medical strategy.
- Leads medical information and scientific engagement activities at professional congresses, ensuring appropriate training, staffing, and documentation.
- Provides medical training for internal teams (Commercial, MSLs, Medical Affairs) on scientific and promotional standards.
Education & Experience
- Advanced scientific degree required (PharmD, PhD, MD preferred).
- At least 6 years of Medical Affairs experience, with PRC/MRC involvement preferred. Senior title may be considered based on tenure and experience, including launch strategy or major regulatory milestone support.
- Deep expertise in clinical development, therapeutic guidelines, competitor landscape, and scientific data interpretation.
- Extensive understanding of FDA promotional regulations, OPDP standards, and medical-legal compliance.
- Excellent written and verbal communication skills with the ability to influence cross-functional partners.
- Strong organizational skills and the ability to manage complex workloads and competing priorities.
Phathom’s Core Values
- Perseverance – With hard work and determination, together we overcome all obstacles
- Humble – We put others first, remain grounded and let our work speak for itself
- Accountable – We are reliable and take personal responsibility in all that we do. We take pride and ownership in our work every day
- Transparent – We say what we mean, debate openly and respectfully, and have no hidden agendas
- Entrepreneurial – We are nimble, agile and embrace innovation. We challenge the status quo, enjoy change and approach problems unconventionally
Working At Phathom
At Phathom, we prioritize the total well-being of our “Phamily” members. Our commitment is reflected in a competitive employee benefits package designed to support employees and their families’ overall well-being, now and in the future, including:
- Highly competitive medical, dental and vision coverage options with low monthly premiums
- Roth & Traditional 401(k) savings plan with annual employer match
- Long-term incentive equity compensation program
- Employee Stock Purchase Plan (ESPP)
- Comprehensive paid leave programs, including:
- 16 weeks of paid parental leave for all new parents
- 4-week part-time Bridge-Back-to-Work Program
- Hybrid and Flex Working Arrangements
- Unlimited Time Off
- 17 paid company holidays in addition to a year-end winter shutdown period
Other Benefits
- Annual Fitness & Wellbeing Reimbursement
- Company-provided Life and Accidental Death & Dismemberment (AD&D) insurance
- Company-provided short and long-term disability benefits
- Company-funded HSA plan
- Accident and Hospital Indemnity insurance
- Employee Assistance Program (EAP)
- Employee recognition program
- Employee discounts
Annual Base Salary: $210,000 - $240,000
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Phathom Pharmaceuticals
$210,000 - $240,000
Dec 22, 2025