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Research Scientist

Temple University
United States, Pennsylvania, Philadelphia
3340 North Broad Street (Show on map)
Apr 11, 2025
Description Grade: T26 The link below will give you information about the University's "T" salary structure. Learn more about the "T" salary structure. A variety of important factors are reviewed by HR when considering salary, including job duties, the applicant's education and experience, all relevant internal equity considerations, department budget, and funding source. The Research Scientist is responsible for independently carrying out a broad range of research tasks for the FCIPM in accordance with established protocols and objectives. This includes conducting tissue culture, Western blot analysis, retroviral transfections, and evaluating DNA damage and repair activity. Additionally, novel treatment approaches will be tested in mouse models of human leukemias and in human leukemia samples. The goal of this research is to assess whether inhibitors of DNA repair pathways can enhance the effectiveness of existing therapies and prevent or delay the progression of leukemia to more aggressive stages. Responsibilities include: Lead and manage the daily operations of the SCMCF, ensuring smooth functioning, compliance with safety regulations, and optimal performance of all equipment. Provide technical guidance and support to faculty, students, and other researchers utilizing the core facility, including designing experiments, performing sample preparation, and analyzing single-cell multiomics data. Oversee the maintenance, calibration, and troubleshooting of all instruments in the facility, ensuring that equipment remains operational and up to date with the latest advancements. Supervise the analysis of complex multiomics datasets using advanced bioinformatics tools and assist investigators with the interpretation and visualization of results Develop and conduct hands-on training sessions for new users, and organize workshops, seminars, and collaborative events focused on single-cell technologies and multiomics analyses. Coordinate multi-disciplinary projects with academic researchers and external collaborators, assisting with experimental design, data collection, and integration of multiomics data from various platforms. Assist in the preparation of grant proposals and reports. Stay current with emerging trends in single-cell and multiomics technologies, and continuously enhance the facility's capabilities by implementing new protocols and acquiring cutting-edge equipment Performs other duties as assigned. Required Education & Experience: PhD in molecular genetics/oncology, biology, genomics, bioinformatics, or a related field and at least 4 years of Postdoctoral experience. . Required Skills & Abilities: Experience in studying DNA repair inhibitors in synthetic lethality in leukemia cells in the context of a single cell approach Must be able to work with potentially hazardous specimens. Ability to keep accurate records of research performed to NIH standards. Ability to operate standard office equipment and software including MS office. Excellent written, oral and interpersonal communication skills. Ability to interact with PIs, students and post-docs. Demonstrated organization skills with the ability to handle multiple tasks Ability to analyze the data, prepare figures and write manuscripts describing scientific achievements This is a grant funded position. Temple University is committed to a policy of equal opportunity for all in every aspect of its operations, including employment, service, and educational programs. The University has pledged not to discriminate on the basis of age, color, disability, marital status, national origin or ethnic origin, race, religion, sex (including pregnancy), sexual orientation, gender identity, genetic information or veteran status. Compliance Statement: In the performance of their functions as detailed in the position description employees have an obligation to avoid ethical, legal, financial and other conflicts of interest to ensure that their actions and outside activities do not conflict with their primary employment responsibilities at the institution. Employees are also expected to understand and be in compliance with applicable laws, University and employment policies and regulations, including NCAA regulations for areas and departments which their essential functions cause them to interact. Temple University's Annual Security and Fire Safety Report contains statistics, policies, and procedures related to campus safety. Click here You may request a copy of the report by calling Temple University's Campus Safety Services at 215-204-7900. Primary Location : Pennsylvania-Philadelphia-Health Sciences Campus (HSC)-Medical Education and Research Building Job : Staff Schedule : Full-time Shift : Day Job Employee Status : Regular